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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f31c21a976f107380ceef68a1f5136be7ab78687aaa211e2beab597f1395780d' 
  AND token = 'ACvRvqRAUdk6wvdVunCYc4TQt8zf0Z4QIDazM0aqkzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}