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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6efa2c64ff20995cf8a6f0b1d3de970d4ac104fa86b9decfb2ee8e9e011cbd66' 
  AND token = 'nJlZbIyKz41HXPYax7OZY8DoSvCKQGUjM/a447Aj06Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}