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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d308c6466711896ab7484a2f49660c9bfabd054b9c5d322ee71b0253288df33' 
  AND token = 'MpBKL0MKycbPJwrc5oNXB2ajY3fCkMMYw2nczgRIhkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}