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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9a3fda60becf795d8d601387d17bf9b1117f1fc40d78d9e92f9725d47d3e409' 
  AND token = '4o+aRzeMvut7BnRqTQEGYeXKJwQruiv1Tn3kTPuPo6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}