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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddf0662b1345a173501d57e63aea75439a16cb426b441a83072b7263dcb0340f' 
  AND token = '+3llIV+wD4sO3BFbdHYsip/LHhgIdQSqHoTG/ap2ItQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}