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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6de6a096802123b84430ce4dc7a94512111be02f88ef2b7ec13cd5b9f7821b7' 
  AND token = 'PutnA4z8wgsi7sMb3DJtb8g6ItP8kuja/yo1kzK32Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}