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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0221076711bb4a25ab2553091415daff3dc37b3c5f0272ed2f5694ccbe2f068a' 
  AND token = 'D8o/dylPjMpesGHl4drNDH0tjL9xelxDaai3utgDMEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}