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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e1490b47a40d11fbad2d3eb3a33b8f2a2ef86012be064de3b9b3d5eb4116ac' 
  AND token = 'mxKLSsNtWWDfTectzHG77xtT9v235dBKQ0uGDm/fkxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}