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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75488f9cd5d37900f223d9bdef83eb7481f4d4b4e050e567396654de7ce7b273' 
  AND token = 'xVvGsVxlYGVcakgNFbx9DBd66SzQL2cnI8SPMga5cyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}