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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '718fbd3d4efa0914024cfce3866d54ac44f9f97462e3390595d0fed9ca314d6d' 
  AND token = 'zOIWjWYMIod9fkc8zKgkq8w6Tqf2Etk+kMPJu1OSPCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}