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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cb08e96487fafbb1063eca9cbe20fac0606b06b5303121bcbacd7460f38dfd' 
  AND token = 'ueD2xRJw3e5OjolBEH/mhRwXO4UldAsP3RR7X4GOe58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}