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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f0565080bb4b80c093fa7803fa4144dfd289fea2de076ea10e037ccf472947' 
  AND token = 'E/bMmXe2Dj+Uvsp8GjdJwBo1LPIQx4kK1Zm4qjkk7KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}