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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9d22974db86d2e15c55497b4dbebcaed4de6f6de4e3656a5c807c678499449' 
  AND token = 'b0WT+08ZgWKa1XPfWs2JBK7h+KlbF7jqbXIq3IZ+TEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}