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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8232b4d8500a4553cb1e385edfa217ee373e2fb571c7c2422a903b28d483245' 
  AND token = '+zB6+xvZuiMZ8HpzevmKTZsYcC4WuQFKr6m1Ab1nnGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}