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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f2b060c93970709aeef3d6d0399008c42912310271b5bfbbc6b3c50b31f5c3' 
  AND token = 'ZlVf+L7pTh0u4gFF5VYopqzlAvlaMgpHOsE4hc3WjyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}