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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0829b33854b6b2a24866e094999fc31d9628d6f32333d6ab225b2a66e19e73ad' 
  AND token = 'RYhNcxvid3jG44ndB5oB6ocwAbRGmxPlB+dJLX9XPrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}