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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd1384cba558486d0bc47bce8680c4a5a7fca7d15800e81c64922bffccd8a842' 
  AND token = '6kFXInWCNEjxY8yj35RXujq7mmMnY4XvE2oPIXpVugQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}