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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7201f781a68e63d122b47d5a08c4f19e83496acfb02e4419fe22936c64d06be7' 
  AND token = 'bgT22cKivLNttkbQ49A+HjThHOLF0bmSk1piHq35PLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}