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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046c3e947da05b91fe35ff151dd075a696e928ee8121fe23204b510f906186df' 
  AND token = '562U4E8rKBpan1lb6DkUp8UI8w2CN7PgVn8i2LJTMh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}