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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62a8825bc759b15cd56c58097aabd851c5ac5ec7d5ba1ad0db992391308f05fd' 
  AND token = '80JZjgstJtoARWp+hKFYFYPDvhozKm8kGn6v69d79C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}