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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '845df4aacc8e172b01b19f97ce350c029bec85f2eaa384c56d6c8f9487577b7a' 
  AND token = 'Ay0zaIXzk1AqtlDw+dzi/pEMfEU/ewfq1cEwGRO3aq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}