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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60653cb550e1782b4a6510de9fa295f11be92e121e0d7740c747fef66c87da14' 
  AND token = 'qFAeO4Zd1dYSkc0Az3xOtBd5GzzXfHpO+fBoh8BBzXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}