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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c475f96e7d01c1ea38845ecc03688cf37e34bd6f9007dcdcc5b355da435b218' 
  AND token = 'rx1BTS6g1v7NBnmsj7cgrhz3V/HGKS8iCdVkZn7T12w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}