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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '397add179ecc8a5f6d65534a3f5ae8fa789c97b0e8449e0553cfe129b1fe480d' 
  AND token = 'Yxl7PxBZwx9UdWAYrY+jQq6330NE3VYLXb3QJ9eoejM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}