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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77bfa697217370f9055690f0c00226d684036372b3d9c3d6200800a6f6664d8e' 
  AND token = 'anTR8s4/o8Foprjm9cjf4Uf//GDEwYi/LEC5vk1Vr3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}