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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5e598d585e6e124a2d35eeb285d48938e21ad1e53d590f731ef518c867f3104' 
  AND token = 'q08bq42fRJayVEpTRZn8GUOSD4WouzDjJStJ38tfeRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}