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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b53dcc91994948536c1821248e7c006330c8d0e3a5fb8ac83d3113e5539c94d' 
  AND token = 'wJDM01WHeTQbRzWsS/2I87SOxP3Jlf5ojG6HexkRwaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}