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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '296456ad885d1a0052c98a01a2a6290b3b77cfa477fc162f953bc1a92d2fec22' 
  AND token = 'FXveYAVNdvu5FAM4sSW1hlMP/RV0++bkP1xsaQGoZ78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}