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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '714dbf33f2c9e27e07e62e0198047c28e481fe4cc31bf1cb5bf4c683f89cb640' 
  AND token = 'qc2jZWhAB3VcXZZH+zuWQYrgO41O4gikIQQ+tbfgQH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}