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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b38d8dd347dcd123564aacdc5b76830c1359d1375eca01270a457c3dbea84c9a' 
  AND token = 'Prur36a7YiId/11JZEns3MGkLt2kG1hbIelYfEp16kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}