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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ac75516926dacb20364c391fb952306397ab445011563573298be1c05804e1' 
  AND token = 'i7Cm4XLevxM1K/42qtjc0VSX+1AA1nlcljye/SN4fwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}