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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd54f9a57842be55cb15596fe21c3afa8077137175e7c089ba819bc665395e438' 
  AND token = 'SX20MTyA/zejyz0jNIba3W5lgxVLkPH9Ek/Y531turM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}