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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eedf310f73f0f091fd90d998781fcf1880753ab234f69070d38e42bb45d6c2b' 
  AND token = 'Vjdqeu3bPa/sIiyejAs7/1cwNy1l+mFRBWfE3qyNqTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}