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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3729e21e58edf2edce1673d27698393826e76b8c9a25642c11100fe3b77feba4' 
  AND token = 'm3Y+B+76vjyZN1mL3ZSnb9xnY/2nivUwh6H0J1ci828=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}