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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216c99ae8d2703952f8508f47ab378b289f09fe57a47a6927a455d173ce51049' 
  AND token = 'zOyS1B96ekMpmmTr1A0zYq08aHmDH0sYDg/tpDPi+Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}