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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed68c9b9f0b83109b8e5628b29d9a0954b53d3d99f75d105f71b670c892d6b74' 
  AND token = '4VpTx7vHovAWcE5kUlVUN5o7HWi9N0/D5UH0me9kXbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}