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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b4c0d6061eb7ae11d0f64a26e1d7293850a7c6d2a25bf75a38b37fc60253d25' 
  AND token = 'K3miMpcSKWQqmIaVcinRXxcBN0n4zfrZiw65tbzt5+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}