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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6e57666543eb17d11a70e57719e6710014bd8e7fe8adefff19e4be969c566b8' 
  AND token = 'bReEGbZxdRtOnrg1dIyFMGiyiITHmbN17542X7e+hU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}