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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeac38871ec74b91c26677b63edd7a10fb7db94052a78bc4e55b49e9adff45cb' 
  AND token = 'loaPO97b3z64wRa+MEWKaFQLeyXYDZ2tg3KlyxFsVQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}