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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e27401fe8f403ed39760e2b49c70e8690f9a02df4ece001e7d1cf0895fb02b3a' 
  AND token = '1yXZwkPfbyqAojcQ3zojqJ1wOqhnOLv33EanXRe5HEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}