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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '109c685a8f6e12196c41c71bdbb7c8f08b4a7c719c99219218530071b579c461' 
  AND token = 'JoyCQXHUcVh2P89y13u+0BZBaXEaJ1RqO0bwum7egCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}