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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4d6718402fb69043b50798cd28b03854ad5dd32d8eb01baf3f85510a97290b' 
  AND token = '3XiL10UsYt0yYZXC0mTf/Ke4Hx6EsvPu86+EZa6JB4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}