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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d02f341304408ed876385bd2a626defd7940cf26f2aa87c1df1037592fbe3d' 
  AND token = 'YhyWG/aFNm6lm+1RRGmT3bi2zFswqCG3SVNOnh2Itbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}