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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043cc6e7425771fc3a42a8c02ab7af605f4d0e3be374f69993517de585274317' 
  AND token = 'IbfQoaYM6DC0XO0Ui9bxtaZ75W1GXF5lBU36u9jl/0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}