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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9d36953c4f1e7e607d54c0dda7da9be8053342db19a156032f043c2b7007aea' 
  AND token = 'tIN/Kx0hbeeR/YAgDbrLEiThH0DEXFcCw3o7WOSMb6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}