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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e1d2f3c3717afe13fc6e40cb8570dc714d467d41cef19e40f363c049d30e38b' 
  AND token = 'DZ7Lpq7VPb54/fE5agZjpGhet2OXU7zoMXJ8EXBdP6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}