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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22190db5395379f027788ff72e777b1703b04f6a414488fa751b406bbd7ddcb' 
  AND token = 'MihBna9MabEY4Cm3VzJWurcIpyBTn7InnFbAwp1Hqjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}