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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e353c5e636d075381f55922393ef73af36895d9f42c9cd9c4508d7df9532e23f' 
  AND token = 'AtSQZ2uyxlIVo5UIOvsb4lbMCu4o8aSALgUgZ9frCcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}