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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f06ea6d84f50d6cd85d283d9f5ec0071653d2671a102b00557e8e3c8ff5b81' 
  AND token = 'O8FKWsH5OqhNcBYzkzBdPVDfrcF5KBlJEkmwdVWf+hY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}