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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a91a8c1c93c3213213ea926cc72fcc299a51f9d9c30688e33da41c7ac40f41e' 
  AND token = 'V/wJKAFBzTcqfzxk6zr5/RsRzXwXdCQ7Fiq3Cspyj5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}